Contra-indications
Do not use in acute glomerular nephritis, in electrolyte diseases, in patients with anuria, or patients that have received excessive doses of cardiac glycosides. Because of the danger of potentiating their toxic effects do not use with aminoglycoside or cephalosporin antibiotics. Allergic reactions have been associated with use with sulphonamides.

Special Warnings
The patient may increase its water intake to compensate for the diuresis. Consideration should be given to restricting water intake if the patient's condition makes such a course appropriate.

Special Precautions
Special precautions for use in animals:
Prolonged dosage may on occasions justify potassium supplementation and thus monitoring for hypokalaemia should be considered, especially if the product is used in conjunction with cardiac glycosides.
Special precautions to be taken by the person administering the medicinal product to animals:
Wear gloves or wash hands immediately after handling tablets. In case of accidental ingestion seek medical attention and show product label and/or pack insert to the doctor.

Adverse Reactions
None reported

Pregnancy and Lactation
The safety of use in pregnancy is not well established and a careful assessment of the likely benefits and potential risks should be made. A deleterious effect on lactation is to be expected, particularly if drinking water is restricted. Furosemide passes into milk, but not to a great extent.

Interactions
Potential interactions with other drugs include ototoxicity with aminoglycosides and nephrotoxicity with cephalosporins. Use in combination with sulphonamide treatment may lead to sulphonamide allergy. There is a possibility of interaction with cardiac glycosides.

Amounts to be Administered and Administration Route
5mg/KgBW, one or two times per day. For patients weighing less than 8Kg dosage with the 20mg tablet (which may be halved) is recommended. Avoid overdosage in weak and old patients.

Overdose
Dehydration and electrolyte depletion may occur. Monitor and correct, as necessary. Dosage higher than that which is recommended, may cause transitory deafness. Cardiovascular side effects may be observed in weak and old patients following overdose.

Withdrawal Periods
None for these species.