Contraindications
Do not use in animals under 6 weeks of age.
Do not use in cats that are suffering from concomitant disease, or are debilitated and underweight (for size and age).
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.

Special warnings for each target species
Animals may be bathed 2 hours after treatment without loss of efficacy.
Do not apply when the animal's hair coat is wet. However, shampooing or soaking the animal 2 or more hours after treatment will not reduce the efficacy of the product.
For ear mite treatment, do not apply directly in the ear canal.

Special precautions for use
Special precautions for use in animals
This veterinary medicinal product is to be applied to the skin surface only. Do not administer orally or parenterally.
Keep treated animals away from fires and other sources of ignition for at least 30 minutes or until the hair coat is dry.
It is important to apply the dose as indicated to minimise the quantity that the animal can lick off. If significant licking does occur, a brief period of hypersalivation may rarely be observed in cats.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
This product is highly flammable; keep away from heat, sparks, open flames or other sources of ignition. Do not smoke, eat or drink while handling the product.
This product is a skin and eye irritant. Wash hands after use and wash off any product in contact with the skin immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water and seek medical advice immediately and show the package leaflet or the label to the physician.
Avoid direct contact with treated animals until the application site is dry. On the day of treatment, children must not handle treated animals and the animals should not be permitted to sleep with their owners, especially children. Used applicators should be disposed of immediately and not left within the sight or reach of children.
People with sensitive skin or known allergy to veterinary medicinal product of this type should handle the product with caution.
Other precautions
Do not allow treated animals to bathe in water courses until at least two hours after treatment administration.

Adverse reactions (frequency and seriousness)
Mild transient alopecia at the site of application has been reported rarely after use of the veterinary medicinal product in cats. Transient focal irritation may also be observed very rarely. The alopecia and irritation are normally self-resolving, but symptomatic therapy may be applicable in some circumstances.
Local temporary clumping of the hair at the application site and/or an occasional appearance of a small quantity of a white powder has been reported rarely. This is normal and will disappear typically within 24 hours of treatment administration and does not affect either the safety or efficacy of the veterinary medicinal product. If significant licking does occur, a brief period of hypersalivation may rarely be observed in cats.
As with other macrocyclic lactones, reversible neurological signs, including seizures, have been very rarely observed after use of the veterinary medicinal product in both dogs and cats.

Use during pregnancy, lactation or lay
The product can be used in breeding, pregnant and lactating cats and dogs.

Interaction with other medicinal products and other forms of interaction
None known

Amounts to be administered and administration route
The product should be administered as a single application of a single dose delivering a minimum of 6 mg/kg Selamectin. When concurrent infestations or infections in the same animal are to be treated with the veterinary medicinal product, only one application of the recommended 6 mg/kg dose should be administered at any one time.

Flea treatment and prevention (cats and dogs)
Following administration of the veterinary medicinal product, the adult fleas on the animal are killed, no viable eggs are produced, and larvae (found only in the environment) are also killed. This stops flea reproduction, breaks the flea lifecycle and may aid in the control of existing environmental flea infestations in areas to which the animal has access.
For the prevention of flea infestations, the veterinary medicinal product should be administered at monthly intervals throughout the flea season, starting one month before fleas become active. Through a reduction in the flea population, monthly treatment of pregnant and lactating animals will aid prevention of flea infestations in the litter up to seven weeks of age.
For use as part of a treatment strategy for flea allergy dermatitis the veterinary medicinal product should be administered at monthly intervals.

Prevention of heartworm disease (cats and dogs)
The veterinary medicinal product may be administered year-round or at least within one month of the animal's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded then immediate administration of the veterinary medicinal product and resumption of monthly dosing will minimise the opportunity for the development of adult heartworms. When replacing another heartworm preventive veterinary medicinal product in a heartworm disease prevention programme, the first dose of the veterinary medicinal product must be given within a month of the last dose of the former medication.

Treatment of roundworm infections (cats and dogs)
A single dose of the veterinary medicinal product should be administered.

Treatment of biting lice (cats and dogs)
A single dose of the veterinary medicinal product should be administered.

Treatment of ear mites (cats)
A single dose of the veterinary medicinal product should be administered.

Treatment of ear mites (dogs)
A single dose of the veterinary medicinal product should be administered. Loose debris should be gently removed from the external ear canal at the time of treatment. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.

Treatment of hookworm infections (cats)
A single dose of the veterinary medicinal product should be administered.

Treatment of sarcoptic mange (dogs)
For complete elimination of the mites, a single dose of the veterinary medicinal product should be administered for two consecutive months.

Method and route of administration:
Spot-on use.
Apply to the skin at the base of the neck in front of the shoulder blades.
How to apply :
Remove the product pipette from its protective package.
1 - Holding the pipette upright, remove the cap.
2 - Invert the cap and place other end back onto applicator tip. Push the cap down to break the applicator seal. Remove the cap prior to treatment application.
3 - Part the hair at the base of your animal's neck in front of the shoulder blades to expose a small area of skin.
Apply the tip of the product pipette directly to the skin without massaging.
Squeeze the pipette firmly to empty the contents in one spot. Avoid contact between the product and your fingers.

Overdose (symptoms, emergency procedures, antidotes), if necessary
No undesirable effects were observed after the administration of 10 times the recommended dose of Selamectin.
Selamectin was administered at 3 times the recommended dose to cats and dogs infected with adult heartworms and no undesirable effects were observed. Selamectin was also administered at 3 times the recommended dose to breeding male and female cats and dogs, including pregnant and lactating females nursing their litters and at 5 times the recommended dose to ivermectin-sensitive Collies, and no undesirable effects were observed.