Advantage 40mg for Small Cats, Small Dogs and Pet Rabbits and Advantage 80mg for Large Cats and Pet Rabbits are clear yellow to slightly brownish solution containing as active substance imidacloprid. Each tube contains 0.4 ml (40 mg imidacloprid) and 0.8 ml (80 mg imidacloprid) respectively plus benzyl alcohol and butylhydroxytoluene (E321) as an antioxidant.

Advantage for cats is used for the prevention and treatment of flea infestations on cats, rabbits and dogs, fleas are killed within one day following treatment. One treatment prevents further flea infestation for up to three to four weeks on cats and up to one week on pet rabbits. The product can be used as part of a treatment strategy for Flea Allergy Dermatitis (FAD). Re-infestation from emergence of new fleas in the environment may continue to occur for six weeks or longer after treatment is initiated. More than one treatment may therefore be required, depending on the level of fleas in the environment. To aid reduction in environmental challenge, the additional use of a suitable environmental treatment against adult fleas and developing stages is recommended. In order to reduce further the environmental challenge, it is recommended that all cats and rabbits in the household are treated.

The product remains effective if the animal becomes wet, for example after exposure to heavy rain, however, re-treatment may become necessary, depending on the presence of fleas in the environment. In these cases do not treat more frequently than once weekly.

Administration to the Cat/Rabbit. Part the hair on the pet’s neck at the base of the skull until the skin is visible. Place the tip of the tube on the skin and squeeze firmly several times to empty the contents directly onto the skin. Correct application will minimise the opportunity for the animal to lick off the product. Apply only to undamaged skin. Do not allow recently treated animals to groom each other. Do not treat unweaned kittens of less than 8 weeks of age or pet rabbits of less than 10 weeks of age.

The product is bitter tasting and salivation may occasionally occur if the animal licks the application site immediately after treatment. This is not a sign of intoxication and disappears within a few minutes without treatment (see dosage and administration). In very rare occasions skin reactions such as hair loss, redness, itching and skin lesions may occur. Agitation and disorientation has also been reported. No incompatibility has been observed between this product at twice the recommended dose and the following commonly used veterinary products: fenthion, lufenuron, milbemycin, febantel, lufenuron, pyrantel and praziquantel.